When newly qualified doctor Andrew Manson takes up his first post in a Welsh mining community, the young Scot brings with him a bagful of idealism and enthusiasm. Both are soon strained to the limit as Andrew discovers the reality of performing operations on a kitchen table and washing in a scullery, of unspeakable sanitation, of common infantile cholera and systemic corruption. There are no X-rays, no ambulances – nothing to combat the disease and poverty.

It isn’t long before Andrew’s outspoken manner wins him both friends and enemies, but he risks losing his idealism when the fashionable, greedy world of London medicine claims him, with its private clinics, wealthy, spoilt patients and huge rewards.